Here’s the news about nitrile: it’s the material of which surgical gloves are made, so it’s non-porous and non-allergenic – what substance could be safer to insert into your asshole? (“M2M keeps your butt’s best interests in mind” is their ad slogan.) PHS International's M2M line has three sizes (4”, 4.5”, and 5”) and thicknesses of anal plug made from nitrile, which is also silicone- and water-based-lube compatible. Clean-up is quick and easy. This new company created by gay men for gay men has very attractive, eye-catching, well-branded packaging; and products are clearly visible in rack displays.