Rick Masters is a sinister doctor who is using an experimental drug on his female victims. The drug is supposed to increase their sexual response to torture. Reporter Sandra Chase and volunteers Victoria and Alison are subjected to bondage, whipping and electric shocks. The storyline began in Doc Bondage and continued in Guinea Pigs. There is no plot here, just scene after scene of graphic bondage. If fans like that sort of thing, they will probably enjoy it.