It's back to the lab for more bondage experimentation. This time, the mad scientist is Travis Lee, with Rick Masters as his willing partner. Rick brings Kimber Allen to the laboratory to make up for her poor test scores. Travis drugs her, then he strips, binds and tortures her. Afterwards, he force-feeds her an experimental drug. When Holly Weston comes looking for her friend, she is also forced into the experiment. Fans of the first two Guinea Pigs videos will probably enjoy this one as well.